Particle Sciences Expands Its Combination Product Capabilities

2008-08-19 12:00:00

    BETHLEHEM, Pa., Aug. 19 /EMWNews/ -- Particle Sciences Inc. has

expanded its Combination Product (drug-eluting polymers) development and

pilot production capabilities with the installation of a compounding,

extrusion and injection molding line. The core of the pilot line,

comprising a Haake twin-screw compounding extruder and Nissei 20T injection

molder, enables the production of high-quality drug loaded polymeric

devices. This addition gives Particle Sciences the ability to go from bench

scale to clinical trial material production. Particle Sciences has recently

completed Phase I of the development of a drug-eluting polymeric vaginal

ring that demonstrated 30-day continuous release of a small molecule API.

Particle Sciences has also developed and successfully demonstrated a

proprietary approach to achieving zero-order release from polymeric drug

delivery devices. "The installation of this line, and our continuing

investment in related intellectual property, increases our capabilities,

and positions Particle Sciences as an innovative developer of drug-eluting

medical devices," commented Dr. Andrew Loxley, Director of New

Technologies. "And coupled with our recently expanded clean room

facilities, will allow us to provide our clients with Combination Product

development services from conception through to clinical trials." For more

information visit

    Particle Sciences is an integrated provider of drug development

services. Particle Sciences focuses on emulsions, gels, particulates and

drug/device combination products with additional specialized capabilities

in topical and mucosal drug delivery. Through a full range of formulation,

analytic, and manufacturing services, Particle Sciences provides

pharmaceutical companies with a complete and seamless development solution

that minimizes the time and risk between discovery and the clinic. The

company was founded in 1991 and is headquartered in Bethlehem,


    Contact: Maureen Cochran 610-861-4701

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