Pharmanex Study Correlates Skin Carotenoids to Overall Antioxidant Health

2008-08-05 06:30:00

Pharmanex Study Correlates Skin Carotenoids to Overall Antioxidant Health

     Research Presented at 15th International Symposium on Carotenoids



    PROVO, Utah, Aug. 5 /EMWNews/ -- Scientists from Nu Skin

Enterprises, Inc. (NYSE: NUS), presented results and consistency of

findings from two large studies at the 15th International Symposium on

Carotenoids in Okinawa, Japan. The research concludes that skin carotenoid

levels measured with the Pharmanex(R) BioPhotonic Scanner correlate with,

and are a good indication of, the body's overall antioxidant defense

system. Carotenoids are pigments that are primarily found in fruits and

vegetables and have been the focus of intense research to determine their

importance in human health.



    "The Pharmanex studies demonstrate that we are accurately measuring

something meaningful with the Skin Carotenoid Score from the Pharmanex

BioPhotonic Scanner," said Joe Chang, Ph.D., chief scientific officer and

executive vice president of product development at Nu Skin Enterprises.

"The conclusions reached from this study are another validation of the

ability of the Pharmanex BioPhotonic Scanner to accurately depict an

individual's overall antioxidant defense system."



    Skin Carotenoids Correlate with Overall Antioxidant Status



    An important finding from the Pharmanex study was a positive

correlation between a person's carotenoid antioxidants, such as

beta-carotene, lutein and lycopene, and levels of other important

non-carotenoid antioxidants, such as vitamins C and E. The research

concludes that skin carotenoid levels are a good marker for an individual's

overall antioxidant status. Antioxidants are known to counter free radical

damage resulting from a variety of sources, including exposure to

pollution, cigarette smoke and sunlight, and being overweight.



    Higher Antioxidant Levels Show Reduced Oxidative Damage



    By measuring a biomarker of oxidative stress (urinary

F2-Isoprostranes), study authors were able to demonstrate that higher skin

carotenoid levels are associated with lower levels of oxidative damage.

This suggests that a healthy antioxidant system offers greater protection

from oxidative stress and can therefore promote better nutritional health.



    BioPhotonic Scanner Measurements Correlate with Industry "Gold

Standard"



    Finally, skin carotenoids measured quickly and painlessly with the

non-invasive Pharmanex BioPhotonic Scanner using Raman Spectroscopy were

shown to be positively correlated with serum carotenoid levels measured by

the conventional method of high performance liquid chromatography (HPLC),

which typically requires a blood draw and specialized analytical equipment.



    "HPLC is the gold standard of carotenoid measurement, yet we've

effectively shown that a non-invasive two-minute measurement with the

Pharmanex BioPhotonic Scanner is just as accurate," said Mark Bartlett,

Ph.D., vice president of Pharmanex global research and development at Nu

Skin Enterprises. "The BioPhotonic Scanner is an innovative business tool

our distributors can use to definitively demonstrate that Pharmanex

nutritional products make a difference for their customer's carotenoid

status and potentially their overall antioxidant health."



    Steve Wood, Ph.D., R.D., Pharmanex senior scientist at Nu Skin

Enterprises, presented the research that was conducted in collaboration

with scientists at several universities.



    About the Pharmanex BioPhotonic Scanner



    More than 8 million people worldwide have been scanned during the past

six years with the Pharmanex BioPhotonic Scanner and are empowered to

develop a personalized antioxidant defense strategy with an individual Skin

Carotenoid Score (SCS). SCS-certified products Lifepak(R) nano and g3 are

sold by Nu Skin distributors with a money-back guarantee. Utilizing

non-invasive Raman Spectroscopy, the Pharmanex BioPhotonic Scanner is a

unique tool that can very effectively demonstrate the bioavailability of

carotenoid-containing supplements. Nu Skin Enterprises is the exclusive

owner of the patented Pharmanex BioPhotonic Scanner technology and received

the 2005 American Business Award for the Most Innovative Company in

recognition of the scanner.



    About the International Symposium on Carotenoids



    The 15th International Symposium on Carotenoids was held June 22-27 in

Okinawa, Japan. The International Symposium was founded in 1966 and every

three years scientists gather for critical presentations and discussions in

the fields of carotenoid research, such as organic and biological

chemistry, physics, medical science, biology and industrial application.

Recent interest in carotenoids as essential nutrients has diversified

carotenoid research into new areas, especially nutrition and medicine. The

International Carotenoid Society exists to provide support and encourage

all areas of carotenoid science.



    About Pharmanex Products



    Pharmanex, the science-based nutritional supplement brand of Nu Skin

Enterprises, helps people build healthier, more productive lives by

providing safe and effective supplements. With more than 100 full-time

scientists employing the 6S Quality Process at three international research

centers, Pharmanex has grown to be a global leader in the nutritional

supplement industry. Superior nutritional products, solutions products and

weight management products are available worldwide. For more information,

select your market at http://www.pharmanex.com.



    The Company



    Nu Skin Enterprises, Inc. is a global direct selling company operating

in 47 markets throughout Asia, the Americas and Europe. The company markets

premium-quality personal care products under the Nu Skin(R) brand, science-

based nutritional supplements under the Pharmanex(R) brand, and technology-

based products and services under the Big Planet(R) brand. Nu Skin

Enterprises is traded on the New York Stock Exchange under the symbol

"NUS." More information is available at http://www.nuskinenterprises.com.





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